Bupivacaine hydrochloride is available in sterile isotonic solutions with and without epinephrine as bitartrate 1. Marapr 2012 volume 16, number 2 view all articles in issue. Marcaine bupivacaine hydrochloride injection 5 numbness. Bupivacaine official fda information, side effects and uses. Marcaine tm bupivacaine hydrochloride injection, usp. Safety data sheet product name marcaine bupivacaine. Bupivacaine hydrochloride monohydrate not listed not listed not listed epinephrine bitartrate not listed not listed not listed emergency overview marcaine bupivacaine hydrochloride with. Bupivacaine hydrochloride 0,1 mgm3 ltel 8hr twa com bupivacaine hydrochloride 1 mgm3 stel 15min com exposure controls use appropriate controls e. Bupivacaine hydrochloride is considered to be highly toxic by ingestion. Comparison of bupivacaine and lidocaine for local anesthesia 16. In nerve blocks, it is injected around a nerve that supplies the area, or into the.
Regulatory information this product has been classified in accordance with the hazard criteria of the controlled products regulations and the msds contains all the information required by the controlled products regulations. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Depending on the dose and route of administration, marcaines onset of action is between one to seventeen minutes and remains effective for two to nine hours. Bupivacaine, marketed under the brand name marcaine among others, is a medication used to decrease feeling in a specific area. Chemical product and company identification manufacturer name and address. Bupivacaine hydrochloride injection usp auromedics. Bupivacaine hydrochloride is 2piperidinecarboxamide, 1butyln2,6dimethylphenyl, monohydrochloride, monohydrate, a white crystalline powder that is freely soluble in 95 percent. Bupivacaine hydrochloride monohydrate usp fagron, inc. Marcaine, sensorcaine bupivacaine hydrochloride is 2piperidinecarboxamide, 1butyln2,6dimethylphenyl. Bupivacaine hydrochloride is a local anaesthetic drug belonging to the amino amide group.
Bupivacaine injection american society of healthsystem. Marcaine bupivacaine hydrochloride with epinephrine injection 1. Its use in this technique has resulted in fetal bradycardia and death. Skin protection if solution contact with unprotected skin is.
Dailymed marcaine spinal bupivacaine hydrochloride in. Find patient medical information for bupivacaine injection on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Bupivacaine hydrochloride monohydrate usp about fagron fagrons strategy is focused on the optimization and innovation of pharmaceutical compounding. Bupivacaine hcl vial 30ml medplus physician supplies. Only select registry of toxic effects of chemical substances rtecs data is presented here. Bupivacaine hydrochloride and epinephrine injection page 6 of 6 section 15. Articles of bupivacaine hydrochloride are included as. Our products are available from authorized distributors. Lidocaine hydrochloride injection, usp, 1% or 2%, contains lidocaine hydrochloride, an amidetype local anesthetic used as a local anesthetic for pain management.
Show this material safety data sheet to the doctor in attendance. Pfizer inc believes that the information contained in this material safety data sheet is accurate, and while it is provided in good faith, it is without warranty of any kind, expressed or implied. Bupivacaine hcl monohydrate 14252803 6270653 100 composition there are no additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as health hazards and hence require reporting in this section. A formulation for preparing bupivacaine hydrochloride 0. Patient information for bupivacaine hydrochloride 2. Rarely, allergictype reactions have been reported during the clinical use of this product reproductive effects decreased pup survival. Therefore, the limiting solubility of the ionized form of bupivacaine from both, the free base and the hc1 salt is about 4050 mgml from ph 1. High quality bupivacaine hcl pharmaceutical anesthetic. Property bupivacaine lidocaine duration of effect is prolonged by use of local anesthetics in. Physicians authorization is required to purchase this item brand name equivalent. Safety data sheet according to federal register vol.
Bupivacaine hydrochloride in dextrose injection usp page 4 of 26 spinal use with the exception of serious diseases of the central nervous system or of the lumbar vertebral column, most. The major advantages compared with other presently used local anesthetics are an increased duration of action and a favorable potency to toxicity ratio. This document has been prepared in accordance with standards for workplace safety, which requires the inclusion of all known hazards of the product or its ingredients. Bupivacaine hydrochloride injection, usp bupivacaine. Bupivacaine hcl monohydrate 14252803 6270653 100 composition there are no additional ingredients present which, within the current knowledge of the supplier and in the concentrations. Bupivacaine liposome injectable suspension exparel. Bupivacaine hydrochloride monograph for professionals. Sensorcaine with epinephrine bupivacaine hcl and epinephrine. Bupivacaine is a widely used local anesthetic agent. Bupivacaine hydrochloride monohydrate ph1481 page 4 of 6 revision.
Bupivacaine liposome injectable suspension monograph updated version may be found at. Sensorcaine bupivacaine hcl is contraindicated in obstetrical paracervical block anesthesia. Msds marcaine bupivacaine hydrochloride injection 101711. Marcaine is contraindicated in patients with a known hypersensitivity to it or to any local. Lidocaine hydrochloride topical solution usp, 4% 2 of 4 extinguishing media. Quantitative mass spectrometric analysis of ropivacaine. Bupivacaine hydrochloride monohydrate sigmaaldrich.
Msds for bupivacaine hydrochloride cas no 14252803 cas no 14252803 other names bupivacaine hydrochloride monohydrate molecular formula c18h28n2o. Dailymed bupivacaine hydrochloride injection, solution. Bupivacaine hydrochloride is an effective local anesthetic agent. We provide the veterinary supplies a clinic needs to support topnotch care in companion animal health.
Bupivacaine investigated as a mutagen, reproductive effector, and tumorigen. Bupivacaine hydrochloride and epinephrine injection, usp. Sigmaaldrich offers a number of bupivacaine hydrochloride monohydrate products. Bupivacaine is often administered by spinal injection prior to total hip arthroplasty. Chemical product and company information manufacturer name hospira, inc. Solutions of bupivacaine hcl containing epinephrine may not be autoclaved.
Bupivacaine hydrochloride pharmaceutical secondary. Regulatory information this product has been classified in accordance. Bupivacaine hydrochloride injection, usp respiratory protection respiratory protection is not needed during normal product use. And address 275 north field drive lake forest, illinois 60045. Sigmaaldrich offers a number of bupivacaine hydrochloride monohydrate. Bupivacaine hcl is available in a sterile isotonic solution with epinephrine as bitartrate 1. Use extinguishing media appropriate to surrounding fire conditions, such as. See actual entry in rtecs for complete information. Chemical product and company identification manufacturer name and address lake forest, illinois 6004 hospira, inc. Solutions of bupivacaine hydrochloride may be autoclaved if they do not contain. It is also commonly injected into surgical wound sites to reduce pain for. Sensorcaine injections contain bupivacaine hcl which is chemically designated.
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